Associate Director, Translational Medicine Lead

Job Title: Associate Director, Translational Medicine Lead

Gaithersburg, MD or South San Francisco, CA

Introduction to role:
Are you ready to turn deep B-cell malignancy biology into decisive clinical action for patients?

Join us in leading translational strategy across a fast-moving portfolio in B-ALL, B-CLL and NHL, connecting mechanism to medicine across multiple modalities including T-cell engaging bispecifics, ADCs, small molecules and cell therapies.

In this role, you will shape the biomarker vision that drives dose, patient selection and combination choices from first-in-human through pivotal studies. You will partner closely with discovery scientists, clinicians and diagnostics experts to build translational data packages that change clinical trajectories. How will you leverage disease linkage, pharmacodynamics and resistance biology to accelerate the next generation of B-cell therapies?

You will be the single point of accountability for translational strategy on assigned programs and trials, ensuring fit-for-purpose assays and data readouts inform rapid, confident decisions. Your work will directly influence which patients benefit, why therapies work, and how we outpace resistance—ultimately advancing our ambition to transform outcomes in hematologic cancers.

Accountabilities:
Translational strategy and delivery: Own and execute end-to-end translational strategies for assigned B-cell malignancy programs from preclinical through Phase 1/2 and, as needed, Phase 3, with clear decision points tied to dose, schedule and patient selection.

Disease linkage and patient selection: Integrate human genetics, expression and clinical data to define indications, stratify patients and refine target populations across monotherapy and rational combinations.
Target engagement and PD: Design and interpret target engagement and pharmacodynamic biomarker readouts to enable >

Date Posted

29-Jun-2026

Closing Date

31-Jul-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.