A Rare Opportunity to Shape the Future of Genomics

Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.

Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.

If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.

We are looking for passionate Clinical Laboratory Associates (CLA) to be responsible for assisting our day-to-day operations, providing equipment maintenance in the clinical laboratory, completing the pre-analytical phase of testing (e.g., plasma and buffy coat isolation), performing quality assurance procedures, while complying with all local, state, and federal laboratory requirements. The Clinical Laboratory Associate (CLA) is an onsite position at Union City and provides a great opportunity for career growth - at BillionToOne, we offer an array of career growth opportunities and clear growth tracks supported by our performance reviews (every 6 months).

Shift Hours: Wed - Sat, 10pm - 8:30am, 4 days/10 hour shifts

Weekday Overnight, 50% shift differential
Weekend Overnight, 55% shift differential

Responsibilities:

Perform isolation procedures according to the laboratorys standard operating procedures to CLA responsibilities
Maintain equipment according to the laboratorys standard operating procedures
Clean labware, equipment, and benches
Prepare documents and binders for equipment and personnel records
Document all corrective actions taken when test systems deviate from the established performance specifications
Perform and document routine preventative maintenance
Prepare reagents required for laboratory preparation
Communicate effectively with coworkers and non- laboratory personnel
Report all concerns of accessioning quality and/or safety to the Laboratory Director, Supervisor, or Safety Officer
Participate in inspection preparation activities
Review of controlled documents as assigned

Qualifications:

Bachelors degree or equivalent in biology or related life sciences field
Excellent attention to detail
Effective written and verbal communication skills
The ability to multitask and work independently

Nice-To-Haves:

Biophysics, Molecular biology (DNA purification, PCR, electrophoresis) or next-generation DNA sequencing laboratory experience
At least 6 months of experience with molecular biology techniques in a research or clinical laboratory
Previous clinical laboratory experience is preferred

Benefits And Perks:

Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
Open, transparent culture that includes weekly Town Hall meetings
The ability to indirectly or directly change the lives of hundreds of thousands patients
Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
Extremely generous Family Bonding Leave for eligible employees (16 weeks, paid at 100%)
Supplemental fertility benefits coverage
Retirement savings program including a 4% Company match
Increase paid time off with increased tenure
Latest and greatest hardware (laptop, lab equipment, facilities)
Daily on-site lunches provided from top eateries
A variety of perks on campus (state of the art gym, restaurant)
Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of (1) competitive base pay, (2) the opportunity for professional growth, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

For this position, we offer a total compensation package of up to $123,892 per year, including an hourly rate (inclusive of shift differential) of $42.71 - $61.50 per hour. Compensation is commensurate with experience and leveling.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

For more information about how we protect your information, we encourage you to review our Privacy Policy.

BillionToOne is a next-generation molecular diagnostics company on a mission to make powerful, accurate diagnostic tests accessible to everyone. Our revolutionary QCT molecular counting technology enhances disease detection resolution by over a thousandfold using cell-free DNA,a breakthrough that has already transformed the lives of over half a million patients worldwide.

Our Impact

Unity Complete is the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample.
Unity Confirmenables non-invasive confirmation for high-risk screening results through the capture of intact circulating fetal cells using BillionToOnes Fetal Cell Capture Technology.
Our Northstar liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care.

Our Growth

From $0 to $400M+ annualized revenue run-rate in just 6 years. In 2025, we completed one of the most successful IPOs for a medical diagnostics company, building on nearly $400M in private funding,including our $130M Series D in 2024 and backed by world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.

Our Recognition

Forbes named us one of America's Best Startup Employers for 2025 and we're Great Place to Work certified, with 100% of our people willing to go the extra mile, even as we've scaled to over 700 employees.

Our Future

Headquartered in Menlo Park with facilities in Union City, CA, and a new lab opening in Austin, TX in 2027, we're continuing to push the boundaries of what's possible in molecular diagnostics. We're just getting started.

Ready to help us change the world, one molecule at a time? Learn more at billiontoone.com

Clinical Laboratory Associate (CLA), Prenatal (Overnight Shift)

BillionToOne

Job Description