Director of Project Management Office, Cell Therapy Technical Operations

At AstraZeneca's, we follow the science to explore and innovate. We are working towards treating, preventing,modifying, and even curing some of the world's most sophisticated diseases. Here we have the potential to grow our pipeline and positivelyimpactthe lives of billions of patients around the world. We are committed to making a difference and have built our business around our passion for science. Now we are fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs.

Position Summary

TheDirector ofProject Management Office, Cell TherapyTechnicalOperations is a highly strategic leadership role responsible forestablishing, digitizing, and leading the Operations branch of the centralized Cell TherapyTechnicalOperations (CTTO) PMO. This leader will set up the PMO's ways of working across CTTO with the ultimate vision of building a PM-enabled, self-sufficient organization.

Reporting into the CMC Portfolio Strategy Cell Therapy organization, this role will oversee high-value Technical and Operational Projects while simultaneouslyestablishingthe standard project management framework,governance,tools, and best practices to beutilizedacross all tiers of theCTTOprojects portfolio.

Byleveragingartificial intelligence and digital automation aligned with AstraZeneca's 2030 ambition, this role will empowertechnicalleaders to manage projects independently,utilizingdedicated PMO resources primarily for complex initiation and planning phases.

This position is based in Gaithersburg, MD.

Responsibilities

• Strategic ProjectExecution: Directly manage or oversee the execution ofcomplex,highly cross-functional above-site Projects ensuring on-time and on-budget delivery.

• Portfolio Visibility & Tracking: Develop, implement, andmaintaina centralized, real-time portfolio dashboard capturing all active projects across the CTTO organization, ensuring full transparency of organizational demand, resources, and strategic alignment.

• PMO Vision & Self-Sufficiency:Design and embed standard project management ways of working across CTTO to foster a PM-enabled, self-sufficient organization. Empower functional Subject Matter Experts (SMEs) and leaders to act asindependent Project Leads, requiring dedicated PMO support for critical lifecycle steps like project initiation and complex planning.

• Digital Transformation & AI Integration:Develop,maintain, and continuously improve the PMO byleveragingcutting-edgedigital solutions and artificial intelligence in alignment with AstraZeneca's 2030 ambition. Partner directly with IT to design, test, and implement custom AI tools and automation strategies that streamline project management workflows.

• Standardization & Best Practices:Act as the authoritative voice for project managementmethodologywithin CTTO. Design, deploy, and govern standardized, highly automated tools (e.g., Project Charters, RAID logs, unified RAG dashboards) to ensure uniform, efficient ways of working across all project tiers.

• Governance:Partner with the CTTO Leadership Team acting as the Project Review Committee (PRC). Facilitate governance meetings to drive>

  Date Posted

  18-May-2026

  Closing Date

  07-Jun-2026

  Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.