Director, Project Team Lead, Early Research

Position Summary:

Quotient is seeking a hands-on strategic leader and operator to lead matrixed project teams comprised of representatives from early genomic science, assay development, high-throughput lab and data science across multiple projects in a scaling biotech environment.

The successful candidate will combine scientific and operational rigor with strong interpersonal and matrixed leadership skills, connecting stakeholders and teams, driving execution, and maintaining alignment across a portfolio of research programs.

This role reports to the Chief Scientific Officer and sits at the intersection of scientific operations, cross-functional execution, and project effectiveness. The incumbent will be accountable for the successful execution of research programs, and improved integration and collaboration across scientific and operational lab-based teams.

Responsibilities:

• Lead a cross-functional matrixed team to develop, execute, and optimize program strategy, timelines, budget, scenario modeling and risk evaluations
• Proactively identify challenges, critical path issues, and opportunities for acceleration; implement and track action plans
• Oversee preparation of program content for gating key decisions, governance review, external communications, and partnership diligence
• Collaborate seamlessly with other project managers to ensure alignment with downstream activities and customers (e.g., target validation and drug discovery)
• Collaborate with Finance on program budget planning, resource management, actuals tracking, and communication of key financial risks
• Maintain full documentation including program status reports, progress summaries, regulatory submissions, and presentations for internal/external stakeholders
• Maintain existing tracking infrastructure for internal capability build projects
• Ensure key stakeholders remain informed and aligned on priorities, timelines, risks, and decisions

Qualifications:

Essential

• PhD with 5-8+ years, or BS/MS with 10+ years in the biopharma industry, preferably in an early therapeutic research or drug discovery setting and ideally with direct experience in the use of genomics or genetics to support drug target identification.
• Minimum 2-5 years of leadership experience with multi-disciplinary project or program teams in an early drug target identification or drug discovery setting.
• Experience in overseeing and integrating wet-lab Research capabilities and computational teams toward complex goals
• Demonstrated track record guiding cross-functional teams to achieve program goals on aggressive timelines in a matrixed or entrepreneurial biotech environment
• Integrative leadership style; able to listen and distill complex problems into a clear solution and direction for cross functional teams
• Excellent interpersonal and communication skills; able to lead and manage without direct line management control
• Strong business acumen, understanding of pre-clinical and clinical drug development strategy, and program management best practices
• Experience managing program budgets and financial reporting in partnership with functional and finance leads

Desirable

• Experience in genomics-based drug target identification research and/or platform-based drug discovery
• Prior success taking programs from research through early clinical development; experience with both small molecules and/or biologics
• Demonstrated success in working with or for rapidly growing, early-stage biotech companies

Values and Behaviors:

• Encourage respectful disagreement and cultivate open-minded, ego-free interactions to continuously push each other towards excellence
• Seek out diverse perspectives; practice active listening and genuine curiosity to ensure all contributions are valued, regardless of source
• Recognize the impact of your behavior, language and attitudes, and strive for balanced, meaningful exchanges that enhance mutual growth and understanding in all interactions
• Use a Quotient-first mindset to guide decision-making; prioritize team over individual success
• Take calculated risks and challenge convention in the quest for exceptional outcomes

About Quotient:

Quotient Therapeutics is a privately-held, early stage company developing breakthrough medicines informed by natural somatic genetic diversity present in patients. Through our work in somatic genomics, we are forging a new status quo for biopharma research and development across a broad pipeline of internal and partnered programs.

The company was founded by Flagship Pioneering, an innovative enterprise that conceives, creates, resources, and grows first-in-category life sciences companies. Flagship Pioneering has created over 100 groundbreaking companies over the past twenty years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna (MRNA), Generate Biomedicines, Sana Biotechnology (SANA), Tessera Therapeutics, Evelo Biosciences (EVLO), Indigo Agriculture, Seres Therapeutics (MCRB), and Syros Pharmaceuticals (SYRS).

Quotient Therapeutics and Flagship Pioneering are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Recruitment & Staffing Agencies:

Quotient Therapeutics (Quotient) and Flagship Pioneering (FSP) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Quotient, FSP or their employees is strictly prohibited unless contacted directly by Flagship Pioneerings internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.