COMPANY DESCRIPTION

Expedition Medicines is a privately held, early-stage biotechnology company pioneering the emerging field of Protein Editing. At Expedition Medicines we create small molecules that edit protein structure and function to unlock presently undruggable targets and a broad array of therapeutic modalities. Our platform integrates novel small molecule chemistry and chemoproteomic discovery technologies with Machine Learning (ML) to enable generative design. Expedition Medicines is backed by Flagship Pioneering, bringing their courage, vision, and resources to guide Expedition Medicines from platform validation to patient impact. We are seeking collaborative, relentless problem solvers that share our passion for impact to join us!

The Role:

Expedition Medicines is seeking a hands-on Vice President of Finance with deep experience in private biotech companies running both pre-clinical and clinical programs. The ideal candidate brings strong finance expertise, technical and operational accounting depth, proven leadership, and a demonstrated ability to build and deploy strategic finance processes at scale. This individual must be comfortable working independently in a resource-constrained environment while overseeing a lean finance and accounting function and also providing strategic financial guidance to the executive team.

The Vice President of Finance will oversee all aspects of accounting, financial operations, and compliance while contributing meaningfully to corporate strategy and long-term planning. This is a key leadership role and is the primary steward of the companys financial strategy, discipline, systems, and governance.

Responsibilities:

Oversee and manage all accounting operations, financial reporting, and internal controls; ensure compliance with GAAP and applicable regulations, manage monthly, quarterly and annual close processes and tax and regulatory filings; initiate/lead financial statement audits

Partner with the CEO and leadership team to develop and refine the companys financial strategy and long-term operating plan; provide scenario modeling within budgets, forecasts, and long-range planning models, and deliver capital allocation recommendations; support fundraising, investor relations, and board-level financial reporting

Implement and maintain innovative and scalable accounting and financial systems, processes and tools; oversee cash flow management, including tracking of R&D expenses, collaboration budgets and operational spend, and lead implementation of accounting and finance systems independent from the Flagship ecosystem

Manage external vendors auditors, accounting consultants, tax advisors, and payroll providers holding them to scope, budget, and timeline

Deploy AI accelerators across finance operations to improve speed, accuracy, and analytical capacity

Qualifications:

Essential

15+ years of progressive finance and accounting experience, including senior leadership roles

Proven track record in a private life sciences/biotech company through growth and successful inflection points

Strong understanding of GAAP and biotech-specific accounting issues, including R&D accruals, intercompany transactions, and collaboration accounting

Experience in leading financial reporting , budgeting and long-range planning processes

Experience and comfort as an individual contributor as well as leading small teams, including external vendors

Demonstrated ability to work independently in a fast-paced, entrepreneurial environment

Desirable

CPA or MBA strongly preferred

Experience supporting fundraising activities (venture capital, crossover, IPO readiness)

Understanding of and interest in utilizing AI and automation for finance

Familiarity with biopharma collaboration accounting and reporting as well as cost modeling for R&D programs

Values and Behaviors:

Encourage respectful disagreement and cultivate open-minded, ego-free interactions to continuously push each other towards excellence

Seek out diverse perspectives; practice active listening and genuine curiosity to ensure all contributions are valued, regardless of source

Recognize the impact of your behavior, language, and attitudes; strive for balanced, meaningful exchanges that build mutual growth and understanding in all interactions

Use a company-first mindset to guide decision-making; prioritize team over individual success

Take calculated risks and challenge convention in the quest for exceptional outcomes

LOCATION:Cambridge, MA

ABOUT FLAGSHIP PIONEERING

Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanitys most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNEs Change the World list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Companys annual list of the Worlds Most Innovative Companies. Learn more about Flagship at .

At Flagship, we accept impossible missions to enable bigger leaps. Our guide us through uncertainty and toward lasting impact.

We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.

We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, FSP) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneerings internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

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Privacy Notice for Applicants: When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact privacy@flagshippioneering.com.

The salary range for this role is $275,000 - $330,000. Compensation for the role will depend on a number of factors, including a candidates qualifications, skills, competencies, and experience. Expedition Medicines currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Expedition Medicines's good faith estimate as of the date of publication and may be modified in the future.