Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three R&D sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide.

Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma.

Legend Biotech is seeking a Head, Business Operations and Alliance Management as part of the Commercial team based in Bridgewater, NJ.

Role Overview

Reporting directly to the President, Carvykti BU, this role serves as the BUs Strategy & Execution Lead, driving alignment, execution, and operational effectiveness across Commercial, GMS, Quality, and Medical Affairs. A core responsibility is managing Legends strategic alliancesensuring strong governance, seamless communication, and proactive issue resolution so both organizations deliver on joint CART objectives.

The role also leads BUwide engagement and communication, fostering clarity, connection, and cultural cohesion across global teams. In parallel, it drives capability building, strengthening organizational readiness, talent development, and crossfunctional effectiveness to support Carvyktis rapid growth and strategic priorities.

Key Responsibilities

Alliance Management:

Lead governance of current and future alliances, ensuring transparent communication, shared accountability, and timely escalation.
Coordinate joint steering committees, joint working teams, and governance bodies to ensure compliance with collaboration agreements and delivery on shared milestones.
Maintain a strong relationship with partner organizations (e.g., Janssen) and serve as a central connective point between Carvykti BU functional stakeholders and alliance partners.
Proactively identify risks, misalignments, or emerging strategic opportunities within collaborations and drive resolution or acceleration initiatives.
Ensure open communication channels across both organizations and consistent partnership health tracking.

Engagement & Communication:

Drive engagement initiatives and forums - town halls, BU business reviews, culture initiatives, leader communications, and crossfunctional alignment sessions.
Serve as a strategic advisor to the BU President on messaging, engagement cadence, and organizational pulse.
Design and lead BUlevel internal communications strategy, ensuring clarity, transparency, and alignment from the President through LT1 and field/operational teams.

Innovation & Strategy Acceleration:

Partner with BU President & LT to shape and drive BU strategic initiatives, including transformation, digital capability scaling, operational innovation, and crossfunctional initiatives.
Monitor industry trends (CART evolution, regulatory updates, partnership models) and translate insights into BU priorities.

Capability Building:

Support BUwide capability strategy (technical, leadership, and operational), to ensure teams are equipped for current and future needs across Commercial, GMS, Quality, and Medical Affairs.
Build mechanisms to measure capability maturity and organizational effectiveness.
Partner with HRBP, OD, and Functional Heads to design learning ecosystems and talent acceleration pathways.
The Head, Business Operations and Alliance Mgmt. exercises independent decision-making authority across strategic and operational domains, including project scope, timelines, resource allocation, and vendor selection. Decisions related to significant budget changes, strategic shifts, or major collaborations require higher-level approvals. This role is expected to proactively identify issues, propose solutions, and guide cross-functional execution with minimal oversight.

Requirements

Advanced degree (MBA, MS) preferred; background in cell therapy, biotech, strategy, or operations strongly desirable.
10+ years in Pharma / Biotech with experience in alliance management, strategy execution, business operations and cross-functional leadership.
Demonstrated success managing highcomplexity external partnerships and governance structures.
Experience working with or leading within matrix organizations across Commercial, GMS, Quality, and Medical Affairs is highly desirable.
Proven track record in driving organizational capability building, communication strategies, or enterpriselevel initiatives.
Strong written and verbal communication skills; executivelevel presence.
Strategic systems thinker with ability to distill complexity and drive clarity.
Exceptional stakeholder management and influence.
Strong program management, change management, and problemsolving capability.
High agility, ability to manage ambiguity, and proactive issue resolution.
Culturally intelligent and globally collaborative.

#Li-JK1

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The base pay range below is what Legend Biotech USA Inc. reasonably expects to offer at the time of posting. Actual compensation may vary based on experience, skills, qualifications, and geographic location. The company reserves the right to modify this range as needed and in accordance with applicable laws.

Other Types of Pay: Performance-based bonus and/or equity is available to employees in eligible roles.

Benefits and Paid Time Off: Medical, dental, and vision insurance as well as a 401(k) retirement plan with a company match that vests fully on day one. We offer eight (8) weeks of paid parental leave after just three (3) months of employment, and a paid time off policy that includes vacation time, personal time, sick time, floating holidays, and eleven (11) company holidays. Additional voluntary benefits include flexible spending and health savings accounts, life and AD&D insurance, short- and long-term disability coverage, legal assistance, and supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance. We also provide voluntary commuter benefits, family planning and care resources, well-being initiatives, and peer-to-peer recognition programs; demonstrating our ongoing commitment to building a culture where our people feel empowered, supported, and inspired to do their best work.

Pay Range (Base Pay):

$256,073—$336,097 USD

Please note: These benefits are offered exclusively to permanent full-time employees. Contractors are not eligible for benefits through Legend Biotech.

EEO Statement

It is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances.

Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company.

For information related to our privacy notice, please review: Legend Biotech Privacy Notice.

Head, Business Operations and Alliance Management

Legend Biotech

Job Description