Head of Make CoE

Job Title: Head of Make CoE

Location: Macclesfield

Hybrid Working: Minimum 3 days per week in the office

Introduction to role:
Are you ready to shape the future of how we make life-changing medicines across a global manufacturing network? As Head of the Make Center of Excellence, you will set the strategy and roadmap that transforms end-to-end Make processes, partnering with sites and central teams to deliver safer, higher-quality, more sustainable, faster and more productive operations. Your leadership will enable our vision for autonomous manufacturing and top-decile performance, turning ambition into outcomes for patients and the business.

Based in Macclesfield (UK), Södertälje (Snackviken and Gärtuna, Sweden), or selected Americas sites, you will orchestrate a complex portfolio through robust governance, enterprise alignment and rigorous Business Process Management. Do you thrive on questioning the status quo, integrating digital and process innovation, and coaching a high-performing team to deliver enterprise-wide results?

Accountabilities:

- Strategy and Roadmap Leadership: Shape, maintain and communicate the Make CoE strategy and multiyear roadmap; ensure clear priorities and measurable value delivery.
- Governance and Alignment: Lead the Make steering committee, co-lead the Make IT Strategy steering committee and actively contribute to Smart Factory and Advanced Data & Analytics governance, achieving enterprise alignment across sites, functions and regions.
- Senior Decision-Making: Formulate compelling business cases, improvement plans and recommendations; present at senior forums to drive decisions that improve quality, performance and productivity.
- Cross-Functional Integration: Partner closely with IT, Data & Analytics, PT&D and GTO to integrate process technology with operational processes, ensuring holistic solutions that scale.
- Smart Factory and Advanced Analytics: Shape and deliver capabilities that advance digital, autonomous and >

Date Posted

22-May-2026

Closing Date

25-Jun-2026Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.