Postdoctoral Research Fellow, BioMedicine Design

Postdoctoral Research Fellow, BioMedicine Design
Last day to apply: July 6, 2026

BioMedicine Design (BMD) group at La Jolla, CA is seeking a highly driven and innovative Ph.D.-level scientist to join our Biotherapeutics Discovery group as a Postdoctoral Research Fellow in driving therapeutic innovation through the development of a next-generation T cell engager (TCE) designed to improve tumor selectivity and minimize on-target, off-tumor toxicity. This is a unique opportunity to be trained at the interface of protein engineering, cell biology, and immunology, to work collaboratively with diverse research teams within Pfizer, and to publish in high-impact journals. By the end of the program, the Postdoc will be proficient in antibody discovery and engineering, cellular assays, and preclinical evaluation, and will be fully prepared to contribute to early-stage therapeutic discovery and modality selection. The ideal candidate should have solid training in molecular biology, cell biology, immunology or structural biology, with a good understanding of biology/oncology.

Key Responsibilities:

• Demonstrate strong technical and scientific rigor in project planning and gap identification

• Proactively conduct literature searches to gather relevant information and form hypotheses for testing experimentally

• Design and produce constructs to further our understanding of underlying biology and mechanism of action; develop and utilize cell-based assays to test hypothesis and screen and rank molecules

• Generate and effectively communicate results regularly at internal meetings, make >Relocation assistance may be available based on business needs and/or eligibility.

  Candidates must be authorized to be employed in the U.S. by any employer.

  U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

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  Research and Development