Postdoctoral Research Fellow - Molecular Cardiology Research Institute Good Lab

Postdoctoral Research Fellow in Vascular Physiology
Molecular Cardiology Research Institute | Tufts Medical Center

The Molecular Cardiology Research Institute at Tufts Medical Center in Boston, invites post-doctoral applications for a position to study arterial and vascular function during ischemic injury in the laboratory of Dr. Miranda Good. The overall objective of the Good Lab is to understand the mechanisms that regulate blood vessel function and inflammation during disease states, such as ischemic stroke and Alzheimer Disease. The lab focuses on evaluating the role and regulation of Pannexin 1, a potential novel therapeutic target, within arterial and venous endothelial cells and how it contributes to the etiology of ischemic injuries and vascular-mediated progression of Alzheimer Disease.

A highly motivated Postdoctoral Research Fellow is sought, ideally with prior experience in
cardiovascular or neurovascular physiology. The laboratory uses state of the art molecular and cellular biology assays, ex vivo vascular function studies, and state-of-the-art mouse models of vascular injury and ischemic injuries to address clinically relevant questions in vascular biology and physiology. Prior experience in pressure myography on resistance arteries and/or survival surgeries in mice or rats is preferred, but not required.

The successful applicant will work closely with the Principal Investigator on research projects studying the vascular mechanisms contributing to detrimental outcomes following an ischemia/reperfusion injury, Alzheimer Disease, or hypertension. As needed, the individual will be required to independently develop protocols and establish new methodologies in the laboratory. The applicant would be intimately involved in writing and presenting new discoveries.

The Molecular Cardiology Research Institute (MCRI) is an internationally known institute with several principal investigators studying diverse topics of molecular medicine. The fellow will work closely with the principal investigator, her lab, and other members of this dynamic research institute. Please visit our website at: www.tuftsmedicalcenter.org/mcri.

Job Profile Summary

​​This role focuses on performing work related to research and development of new products, innovation, and improvement of products and processes. In addition, this role focuses on performing the following Research Programs and Projects duties: Supports the development of new products and innovation. Includes Clinical roles focused on research projects. Positions in this family perform basic, translational, and/or clinical research towards solving a specific problem for an entity or community.A professional individual contributor role that may direct the work of other lower level professionals or manage processes and programs. The majority of time is spent overseeing the design, implementation or delivery of processes, programs and policies using specialized knowledge and skills typically acquired through advanced education. An experienced level role that applies practical knowledge of job area typically obtained through advanced education and work experience. Works independently with general supervision, problems faced are difficult but typically not complex, and may influence others within the job area through explanation of facts, policies and practices.

Job Overview

This positionleads and contributes to cutting-edge research projects aimed at improving healthcare outcomes. Individuals in this position work closely with a team of researchers and healthcare professionals to conduct innovative studies and contribute to the advancement of knowledge in the field. This position offers a unique opportunity to engage in impactful research, collaborate with interdisciplinary teams, and further develop your research skills in a healthcare setting.

Job Description

Minimum Qualifications:

1. PHD in a relevant field of study OR M.D.

2. Prior experience in healthcare research.

Preferred Qualifications:

1.Record of publication in relevant field of study.

Duties and Responsibilities: The duties and responsibilities listedbelow are intended to describe the general nature of work and are not intended to be an all-inclusive list. Other duties and responsibilities may be assigned.

1. Conducts independent research projects within the healthcare field, under the guidance and mentorship of senior researchers.

2. Designs and implements research studies, including experimental protocols, data collection methods, and statistical analysis plans.

3. Analyzes and interprets research data, using appropriate statistical techniques and software.

4. Prepares research findings for publication in peer-reviewed journals and present at conferences and scientific meetings.

5. Collaborates with other researchers and professionals to develop and refine research hypotheses, study designs, and methodologies.

6. Stays updated with the latest advancements and breakthroughs in healthcare research and apply relevant knowledge to ongoing projects.

7. Assists in securing research funding by contributing to grant writing and research proposal development.

8. Collaborates with healthcare professionals and institutions to collect clinical data and samples for research purposes.

9. Contributes to the development and validation of new diagnostic tools, treatments, and interventions.

10. Participates in the preparation of research reports, progress updates, and grant applications.

11. Mentors and provide guidance to undergraduate and graduate students involved in research projects.

12. Collaborates with industry partners to translate research findings into practical applications and technologies.

13. Collaborates with regulatory bodies and ethics committees to ensure compliance with research protocols and regulations.

14. Contributes to the dissemination of research findings to healthcare professionals, policymakers, and the general public through various channels, such as seminars, workshops, and publications.

15. Maintainsaccurate and organized records of research data, protocols, and results, ensuring data integrity and confidentiality.

Physical Requirements:

1.Typical clinical and administrative office setting.

Skills & Abilities:

1. Demonstrated experience in research design, data collection, statistical analysis, and scientific writing.

2. Proficiency in statistical software packages (e.g., SPSS, SAS, R) and data management tools.

3. Strong analytical and critical thinking skills, with the ability to interpret complex data sets.

4. Excellent verbal and written communication skills, including experience presenting research findings to diverse audiences.

5. Ability to work independently and collaboratively within a team environment.

6. Knowledge of ethical guidelines and regulations related to healthcare research.