Principal Scientist, Translational Modeling & Decision Science
Flagship Pioneering, Inc.
Cambridge, MA USA
Full-Time
$179,000
OfficeSenior
Pioneering Intelligence builds on Flagship Pioneerings legacy of founding cutting-edge science and computational ventures, harnessing recent advances in AI, machine learning, and data to accelerate fundamental research and create a portfolio of AI-first companies. As part of Flagships integrated model of science, entrepreneurship, and capital, it transforms breakthrough ideas into world-changing companies, elevating the AI advances happening across the ecosystem in human health, sustainability, and beyond.
Pioneering Intelligence (PI) is building AI systems that accelerate translational decision making. This forward-deployed role bridges the gap from capability to impactby leveraging PI technologies to take on translational challengesacross Flagships therapeutic portfolio, delivering value through programs and business decisionswhile returning insights that improvethe AI platform.
The successful candidate will reduce the scientific uncertainty behind Flagships drug development and investment decisions through mechanistic modeling and quantitative analysis.
The individual will work across the portfolio rather than within a single program, taking on diligence questions, milestone decisions, and competitive assessments as they arise, matching analytical rigor to the consequence of each decision, and flagging when one programs finding is relevant to another. They will also serve as an expert test user for the Applied AI and Engineering teams, feeding field discoveries back as product requirements.
The role owns the credibility of its analyses: transparent uncertainty, defensible assumptions, and results a stakeholder can carry into their own decision. The role also owns the identification of opportunities to close comprehension and trust gaps associated with complex agentic work products.
Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanitys most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.
Flagship has been recognized twice on FORTUNEs Change the World list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Companys annual list of the Worlds Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.
At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.
We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.
We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.
Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, FSP) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneerings internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.
#LI-MB1
The salary range for this role is $179,000 - $236,000. Compensation for the role will depend on a number of factors, including a candidates qualifications, skills, competencies, and experience. Pioneering Intelligence currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Pioneering Intelligence's good faith estimate as of the date of publication and may be modified in the future.
Privacy Notice for Applicants: When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact privacy@flagshippioneering.com.