Project Physician

Job title: Project Physician

Location: Siena, Italy

Employment type: Permanent, full time

Closing date for applications: 19 June 2026

Position Summary

To Lead Clinical development of One or more GVGH Vaccine Development Programmes through the design and set-up of GVGH-managed clinical trials To serve as lead author or key contributor of clinical and epidemiology plan and clinical documents (e.g., clinical trial protocols, reports and publications, integrated clinical documents for regulatory submissions etc.) and to have medical monitoring responsibility for clinical trials of GVGH vaccine project(s). In order to ensure the high quality and on-time delivery of all clinical data that will allow demonstration of Proof-of Concept of GVGH candidate vaccines in line with the clinical development plan, good clinical practices (GCP), and GSK Vaccines/ GVGH standard operating procedures (SOP). To be a member of the cross functional Safety Review Team coordinated by SERM

Responsibilities

Work in a Clinical Development sub-team of clinical and regulatory colleagues (clinical development, clinical operations, biostatistics & regulatory associates), and in collaboration with non-CDRA members of the GVGH Project Team(s), with the responsibility to author clinical development plans, design clinical trial protocols, write Investigator Brochures, clinical study reports and publications of the project(s) to high scientific, operational and ethical standards.
• Address scientific and medical issues related to trials of the project(s) in GVGH.
• Be responsible (or provide oversight of delegated CRO medical monitoring team) for Medical Data Listing review, ensuring medical consistency within trial and across trials within the project.
• As a member of the Safety Review Team, be accountable (through providing oversight if applicable of delegated CRO medical monitoring team) for medical assessment of serious adverse events, adverse events of special interest (AESI’s) and other events occurring during clinical trials and pay attention to potential safety signals.
Additionally, participate in individual case safety report compliance activities and take the necessary corrective actions.
• Handling and/or coordinating studies with human biological samples using GVGH WS/GSK policies.
• Support the Senior project physician Lead in representing GVGH in meetings with health authorities and the scientific community, network with thought leaders and international agencies, on specific GVGH vaccines related project matters.
• Contribute to creation, review and revision of standards (e.g., SOPs, Work Instructions) on clinical development, regulatory and drug safety activities.
• Maintain/expand knowledge in vaccines, clinical trial methodology, and drug safety competencies including national and international regulations and Global Safety policies/procedures.
• Serve as the principal liaison to GVGH Safety and Data Management Committees: SRT, Internal Safety Review Committee (iSRC) and Independent Data Monitoring Committee (IDMC).
• Where applicable, lead matrix team, to author program strategy, clinical development plans and design clinical trial for governance meetings and ensure consistency of data within program and across projects. Reporting accountability will be to the Senior Project Physician Lead.

Budget, resourcing and timing
• Supports the clinical team to consistently achieve high standards and attainment of project timelines in global programs.
• Interfaces with the SDL to ensure milestone realization and resource optimization.

Why you?

Basic Qualifications & Skills

We are looking for professionals with these required skills to achieve our goals:

• Doctor of Medicine with advanced university degree (Masters or PhD) and Board certification. In order of preference: vaccinology, infectious diseases, global health, pediatrics.

• At least 2-3 year experience in industry clinical development and/or drug safety in a pharmaceutical company or 10 years working in a scientific or medical Institution.

• Medical and scientific knowledge and track-record in infectious diseases through training and practice and the ability to function independently while supervised with significant experience in clinical development and drug safety in academia or industry.

• Demonstrated experience and initiative in finding solutions to challenges in the clinical development space in LMICs is a key attribute.

Preferred Qualifications & Skills

If you have the following characteristics, it would be a plus:

• Innovative problem solving is a desirable requirement due to the need to provide balanced clinical and ethical guidance, particularly in the sites and countries where some of the GVGH clinical trials may take place.

• Strong clinical leadership and excellent interpersonal and communication skills to work effectively with internal GVGH/GSK project teams, CRO partners, external clinical site teams and international scientific and funding stakeholders.
• Proven ability to interact with tact, respect and cultural sensitivity with diverse stakeholders, including opinion leaders, doctors, patients, health workers and community leaders in LMIC settings.
• High level of impact and accountability for project success in clinical development and drug safety, including independent issue resolution and decision-making.
• Demonstrated ability to generate, interpret and communicate complex clinical data, taking end-to-end responsibility for results, reporting and scientific dissemination with limited supervision.

What we offer:

• Permanent contract in a very Inclusive environment

• Flexible Benefits

• Company Healthcare Plan

• Integrative pension fund

• Employee Assistance Programme

• Prevention services and vaccination clinic

• Tax assistance

• Local nursery agreement

• Postal service, laundry, shoe repair and tailoring

• On Site Gym

• On Site canteens and coffee corners

• Free company bikes and shuttle

Please take a copy of the Job Description, as this will not be available post closure of the advert.
When applying for this role, please use the ‘cover letter’ of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

Italian Salary Range / Fascia retributiva in Italia: EUR 60,000 to EUR 100,000The annual gross base salary range for new hires in this position is listed above for each applicable location. These ranges take into account a number of factors including the candidate’s skills, experience, education level and the market rate for the role. In addition, this position may offer an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. More detailed information on the total benefits package will be supplied during the recruitment process. This role is available for applicants from multiple locations, and therefore salary ranges for certain locations are also shown. Salary ranges for other locations are shown because some markets have pay transparency laws that require salary information on job postings, and those locations are potential job sites for this role. If salary ranges are not displayed in the job posting for a specific location or country, the relevant compensation will be discussed during the recruitment process. Please note salaries vary by country based on the candidate’s skills, experience, education level and the market rate for the role. Offers are typically made within the advertised range based on the candidate’s skills, experience and qualifications, with the upper end generally reserved for highly experienced candidates or other exceptional circumstances aligned with these criteria.La fascia salariale della Retribuzione Annua Lorda (RAL) per i nuovi assunti in questa posizione è indicata sopra per ciascuna sede applicabile. Queste fasce tengono conto di diversi fattori, tra cui le competenze, l'esperienza, il livello di istruzione del candidato e le condizioni di mercato per il ruolo. Inoltre, questa posizione potrebbe prevedere un bonus annuale e la partecipazione al nostro programma di incentivazione a lungo termine basato sull’assegnazione azioni, in funzione del livello del ruolo. Informazioni più dettagliate sull’intero pacchetto retributivo e sui benefit saranno fornite durante il processo di selezione. Questo ruolo è aperto a candidati basati in diversi paesi; per tale motivo sono indicate le fasce retributive relative a ciascun paese. La pubblicazione di tali fasce, per altri paesi, che sono possibili sedi lavorative per questa posizione, risponde a normative locali in materia di trasparenza retributiva, che richiedono l’indicazione delle retribuzioni negli annunci di lavoro. Qualora per una specifica sede o paese non sia indicata una fascia retributiva, le relative condizioni economiche saranno discusse nel corso del processo di selezione. E’ importante considerare che le retribuzioni variano da paese a paese in base alle competenze, all’esperienza, al livello di istruzione del candidato e alle condizioni di mercato per il ruolo. Le offerte vengono generalmente formulate all’interno della fascia indicata, tenendo conto delle competenze, dell’esperienza e delle qualifiche del candidato; il limite superiore è di norma riservato a candidati con un’esperienza particolarmente consolidata o a circostanze eccezionali coerenti con tali criteri.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

Should you require any specific adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on ita-inclusion.recruitment@gsk.com.

Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

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