Senior Director Clinical Biomarkers, BioPharma Business Development
Natera
San Francisco, CA; US Remote
Full-Time
$248,100
RemoteDirector
The Senior Director Clinical Biomarkers, BioPharma Business Development will provide strategic,
scientific, and organizational leadership across a broad oncology diagnostics portfolio. This
executive will be responsible for defining and advancing biomarker and translational medicine
strategies across early- and late-stage BioPharma collaborations in support of Nateras strategic
goals eg TOMR and surrogacy in collaboration with Nateras lifecycle and clinical development
teams.
The ideal candidate will bring deep expertise in oncology drug development, biomarker
strategy, and translational research, with experience spanning Phase 13 studies and multiple
therapeutic modalities, including immunotherapy, targeted therapy, and antibody-drug
conjugates.
Key Responsibilities
Lead translational medicine and clinical biomarker strategy across oncology programs
within and beyond the BioPharma BD portfolio.
Define and oversee biomarker plans supporting late-stage development in solid tumors
within the BioPharma space (Pharma Lab Services, BD partnerships) including assay
strategy, translational endpoints, data generation, data interpretation, publication
planning, and regulatory filing support.
Partner closely with clinical development, bioinformatics, medical affairs, regulatory,
diagnostics, and commercial teams to ensure assay development portfolio and
biomarker strategies are aligned with overall BioPharma BD needs.
Work with external partners on their Natera-supported translational research efforts to
help them leverage Natera capabilities to optimize the value of their projects: these may
include identifying novel targets, characterizing resistance mechanisms, developing
novel predictive biomarkers and next-generation clinical tools, including blood-based
biomarkers, digital pathology, radiomics, and AI/ML-enabled approaches.
Support development and lifecycle strategies that enable successful product
differentiation, launch readiness, reimbursement, and broader clinical adoption.
BioPharma Deliverables
Contribute to study design and evidence-generation plans that support our BioPharma
efforts across BD, Pharma Lab Services, and internal R&D.
Work with the RWD, AI, and bioinformatics teams to develop use cases for existing data
and build out new concepts for new data types as they are created.
Apply translational insights to inform patient selection, development decisions, and
clinical differentiation strategies for our customers.
External Relationships & Strategic Engagement
Establish and lead strategic collaborations with BioPharma partners, academic
institutions, cooperative groups, scientific consortia, and key opinion leaders.
Represent the company in external scientific and clinical initiatives that shape the future
of biomarker-enabled oncology development.
Build productive external partnerships that accelerate innovation, evidence generation,
and adoption of novel translational approaches.
External Scientific Presence
Serve as a visible scientific leader through publications, invited presentations, advisory
participation, and broader thought leadership in oncology and precision medicine.
Maintain strong credibility in the external scientific community, with the ability to
engage effectively with academic leaders, consortia, and industry partners.
Contribute to the companys scientific reputation through high-impact external
presence and publication strategy.
Preferred Qualifications
Advanced degree in a relevant scientific discipline; PhD, MD, DVM, or equivalent
strongly preferred.
15+ years of relevant experience in translational medicine, clinical biomarker
development, oncology drug development, or related fields.
Significant experience in biomarker-driven clinical development and medical affairs
across early- and late-stage oncology programs.
Demonstrated success in building external scientific relationships and representing
organizations in high-profile external settings.
Strong record of scientific leadership, cross-functional collaboration, and strategic
execution.
This range reflects a good-faith estimate of the base pay we reasonably expect to offer at the time of hire. Final compensation will vary based on experience, qualifications, and internal equity considerations.
This position is also eligible for additional compensation and benefits through Nateras robust Total Rewards program, including:
Annual performance incentive bonus
Long-term equity awards
Comprehensive health benefits (medical, dental, vision)
401(k) with company match
Generous paid time off and company holidays
Additional wellness and work-life benefits
Natera is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, womens health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.
The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, youll work hard and grow quickly. Working alongside the elite of the industry, youll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.
Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!
For more information, visit www.natera.com.
Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.
All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.
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