Senior Manager, Medical Affairs

Patients are at the heart of everything we do. Aortic stenosis impacts millions of people globally, yet it often remains under-diagnosed and under-treated. Edwards’ groundbreaking work in transcatheter aortic heart valve replacement (TAVI) pioneered an innovative, life-changing solution for patients by offering aortic valve replacement without the need for open heart surgery. Our Transcatheter Heart Valve (THV) business unit continues to partner with cardiologists and clinical teams to transform patient care with devices supported by clinical evidence. It’s our driving force to help patients live longer and healthier lives. Join us and be part of our inspiring journey.

THV Medical Affairs supports independent research and education with grants for Health Care Organizations (HCO). The main purpose of the role is managing the full lifecycle of grant agreements and associated tasks for Health Care Professionals (HCPs), HCOs and Professional Conference Organizers (PCO) and other external stakeholders along with processing payments while optimizing workflows and processes within the team.

Our Medical Affairs team have an opening for a Senior Manager, Medical Affairs to join our team focused in our Transcatheter Heart Valve business.

This role is based in Czech Republic. This role can be hybrid or office based in Prague with 30% national and international travel as required.

Overview

This role is responsible for managing Medical Affairs grants, ensuring high-quality scientific engagement, evidence generation, and results dissemination. The role combines medical information leadership, scientific communication and oversight of research and publication activities, including collaboration with CROs and external stakeholders.

In addition, the role supports grant lifecycle management, evidence generation strategy, and publication planning, contributing to advancing clinical evidence and improving patient outcomes.

How you will make an impact:

Evidence Generation & CRO Collaboration

• Support clinical research and evidence generation activities, including registries, investigator-initiated studies, and post-market studies

• Collaborate with Clinical Research Organizations (CROs) on study execution, data quality, and timelines

• Provide medical oversight and input into study design, protocols, endpoints, and data interpretation

• Ensure adherence to Good Clinical Practice (GCP) and regulatory requirements

Grants & Research Support

• Support the management of the full lifecycle of Medical Affairs grants, including educational and research funding

• Coordinate with HCPs, HCOs, and external partners, ensuring compliance and documentation

• Track deliverables, budgets, and reporting requirements

• Contribute to evidence generation strategy through grant-supported activities

Scientific Publications & Dissemination

• Lead and contribute to scientific publications (abstracts, manuscripts, congress presentations)

• Support medical writing activities, ensuring high-quality, evidence-based outputs

• Develop and execute a publication and dissemination plan aligned with medical strategy

• Coordinate with internal and external stakeholders (authors, investigators, CROs) to ensure timely delivery of publications

• Track and communicate publication metrics and impact1. Medical Information & Scientific Content

• Plan, lead, and execute scientific content development in a fast-paced environment, ensuring timely delivery within defined scope

• Provide scientific and medical expertise to cross-functional teams and stakeholders

• Ensure scientific accuracy, compliance, and alignment with regulatory and company standards

Medical Affairs Projects & Operations

• Lead Medical Affairs projects, including research projects, educational initiatives, and cross-functional activities

• Apply strong project management principles to ensure delivery of complex initiatives (timelines, risks, resources)

• Collaborate with Clinical, Marketing, Regulatory, and Market Access teams to align strategy and execution

• Drive process optimization and operational excellence within Medical Affairs

Evidence Generation & CRO Collaboration

• Support clinical research and evidence generation activities, including multicentric registries, investigator-initiated studies, and post-market studies in Europe, Middle East, Africa, Canada and Latin America

• Collaborate with Contract Research Organizations (CROs) on study execution, data quality, and timelines

• Provide medical oversight and input into study design, protocols, endpoints, and data interpretation

• Ensure adherence to Good Clinical Practice (GCP) and regulatory requirements

Scientific Publications & Dissemination

• Lead and contribute to scientific publications (abstracts, manuscripts, congress presentations)

• Support medical writing activities, ensuring high-quality, evidence-based outputs

• Develop and execute a publication and dissemination plan aligned with internal strategy

• Coordinate with internal and external stakeholders (authors, investigators, CROs) to ensure timely delivery of publications

• Track and communicate publication metrics and impact

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Compliance & Quality

• Ensure all activities comply with regulatory requirements, MedTech guidelines, and internal policies

• Maintain high-quality documentation and audit readiness

• Support quality-related processes and inspections

What you will need:

• Master’s Degree or PhD Degree (ideally in life sciences/medicine/pharmacy) with broad relevant experience

• Strong background in Medical Affairs, clinical research, or scientific roles in MedTech/pharma

• Demonstrated experience with: Clinical research and CRO collaboration; Scientific publications and medical writing; Medical advisory and scientific exchange as well as Project management

• Previous experience working in Structural Heart Disease or complex Cardiology filed would be highly desirable

What else we look for:

Project & Stakeholder Management

• Proven project management skills with ability to manage multiple initiatives simultaneously

• Ability to lead cross-functional teams and influence stakeholders

• Strong organizational and prioritization skills

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Scientific & Medical Expertise

• Strong scientific background with ability to interpret clinical data and translate into practice

• Experience in evidence-based medicine and publication strategy

• Expertise in scientific communication

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Project & Stakeholder Management

• Proven project management skills with ability to manage multiple initiatives simultaneously

• Ability to lead cross-functional teams and influence stakeholders

• Strong organizational and prioritization skills

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Collaboration & Communication

• Excellent communication and interpersonal skills, including KOL engagement

• Ability to negotiate, influence, and build long-term partnerships

• Experience working in international and cross-functional environments

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Technical & Compliance Knowledge

• Advanced proficiency in Microsoft Office Suite and business tools (e.g., Salesforce, Power BI) as well as literature databases like Embase, Sciencedirect or PubMed

• Strong understanding of regulatory requirements, GCP, and compliance frameworks

• Knowledge of event management, and scientific congress activities

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Key Behaviours

• Strong attention to detail and commitment to scientific excellence

• Ability to work in a fast-paced, matrix environment with competing priorities

• Proactive, solution-oriented mindset

• High level of integrity and compliance awareness

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Impact

This role contributes directly to:

• Generation and dissemination of high-quality clinical evidence

• Scientific credibility of Medical Affairs

• Improved patient outcomes through education and innovation

What is it like to work at Edwards Lifesciences in the Czech Republic?

As a global leader in patient-focused medical innovations, we offer rewarding opportunities and exciting challenges in a truly international, dynamic and friendly work environment.

We are committed to fostering a diverse and inclusive work environment where all employees can grow, personally and professionally. To achieve this, we offer on-the-job development, training opportunities and the support and guidance provided by dedicated employee groups (the Edwards Network of Women, Edwards Foundation charity team, sustainability activities, and others).

Edwards Lifesciences in the Czech Republic also offers the following benefits:

• Competitive Compensation and Benefits package

• Flexible working hours, remote working

• Pension Plan Risk Life Insurance

• Virtual Medical Clinic (online access to healthcare)

• Meal Benefits

• Service Awards

• Enhanced Sick Leave Benefits

• Flexible Benefit Plan (Cafeteria)

• Employee Stock Purchase Program

• Employee Assistance Program

• Comprehensive Wellness Program including onsite gym, Yoga, Pilates or SM System classes, massages, fresh fruit in the office, healthy lifestyle workshops, educational events, charity activities and much more.

Benefits are regulated by an internal policy which contains the full details regarding the entitlement and conditions for the benefits. Benefits policy and components may vary by location.