Regeneron’s Product Biochemistry in Tarrytown, NY is seeking a motivated and innovative Senior Scientist to drive late-stage development (Phase II through commercialization) of biologics. You will develop and deploy analytical methods and purification strategies, enrich and characterize product variants, and help onboard new technologies that deepen product understanding and improve processes across the pipeline. This role is for you if you are scientifically creative, hardworking, efficient, flexible, and able to perform key responsibilities in a fast-paced, team environment.
Key Responsibilities:
- Develop analytical methods and purification protocols to support extended characterization of therapeutic proteins and gene therapy vectors.
- Conduct biochemical/biophysical characterization to support development, regulatory submissions, and commercialization.
- Apply DOE, advanced statistics, and risk assessments to evaluate and optimize methods and processes.
- Author high-quality technical documents (protocols, reports, memos) and contribute to regulatory sections and publications. Ensure timely documentation of experiments following established SOPs and guidelines.
- Maintain instruments, troubleshoot issues, and improve lab/data workflows within your area of expertise. Adhere to procedures, guidance, and best practices to ensure lab safety.
- Proactively identify process improvement opportunities across Product Biochemistry and Regeneron and help drive implementation.
A Typical Day in the Role Might Look Like:
- Design and execute experiments to enrich, purify, and characterize size/charge variants, complexes, and high-concentration formulations.
- Integrate learnings from internal data and external literature to make science-based study design recommendations.
- Documents experiments, results and findings in electronic laboratory notebook; presents work at group and department meetings; contributes to drafting of protocols, method development reports, regulatory submission sections, and peer-reviewed articles for publication.
- Lead or participate in technology initiatives and continuous improvement projects; may also mentor and guide junior analysts in a matrix-based environment.
- Maintain instruments, troubleshoot instrumental/experimental problems, and order/maintain supplies.
This Role Might Be For You If:
- Possess strong lab skills in protein separation, purification, and tangential flow filtration (TFF). Possess skills in protein/product identification using mass spectrometry.
- Thrive in a fast-paced, team environment and can also work independently across multiple projects.
- Demonstrate initiative, calculated risk-taking, and a passion for innovation and continuous improvement.
- Communicate clearly, manage projects effectively, and solve complex problems with href="https://careers.regeneron.com/en/working-at-regeneron/total-rewards/">https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter.
Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.
As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.
For jobs in Canada: this posting is for an existing position.
Salary Range (annually)
$109,900.00 - $179,300.00
